M1: Preclinical evaluation of a vaccine strategy based on conserved conformational epitopes of the HIV envelope glycoprotein
Dokumentation 1997–2006
Projektleiter:
Prof.Dr.Valerie Bosch
DKFZ, Tumorvirologie F 0200
Im Neuenheimer Feld 242
69120 Heidelberg
Projekttitel:
Preclinical evaluation of a vaccine strategy based on conserved conformational epitopes of the HIV envelope glycoprotein
Projektdauer:
01/2002 - 07/2007
Veröffentlichungen:
- Denise Holtkotte, Tanya Pfeiffer, Thorsten Pisch and Valerie Bosch
Selection and Characterization of a Replication-Competent Human Immunodeficiency Virus Type 1 Variant
Encoding C-Terminally Truncated Env
AIDS Research and Human Retroviruses, Vol. 22, Number 1, 2006, pp. 57-65 - Tanya Pfeiffer, Thorsten Pisch, Gerard Devitt, Denise Holtkotte, Valerie Bosch
Effects of signal peptide exchange on HIV-1 glycoprotein expression and viral infectivity in mammalian cells
FEBS Letters 580 (2006) 3775-3778 - Gerard Devitt, Vanessa Emerson, Thorsten Pisch, Oliver T. Keppler, Valerie Bosch
Analysis of the exposure of induced HIV glycoprotein epitopes in a potential HIV pseudovirion vaccine
Vaccine 25 (2007) 2161 - 2167 - Gerard Devitt, Vanessa Emerson, Denise Holtkotte, Tanya Pfeiffer, Thorsten Pisch, Valerie Bosch
Incorporation of chimeric HIV-SIV-Env and modified HIV-Env proteins into HIV pseudovirions
Virology 361 (2007) 465 - 471 - Gerard Devitt, Mini Thomas, Alexander M. Klibanov, Tanya Pfeiffer, Valerie Bosch
Optimized protocol for the large scale production of HIV pseudovirions by transient transfection of HEK293T cells with linear fully deacylated polyethylenimine
Journal of Virological Methods 2007 - Valerie Bosch, Tanya Pfeiffer, Gerard Devitt, Ina Allespach, Thomas Ebensen, Vanessa Emerson, Carlos A. Guzman, Oliver T. Keppler
HIV pseudovirion vaccine exposing EBv “fusion intermediates” – Response to immunisation in human CD4/CCR5-transgenic rats
Vaccine 27 (2009) 2202-2212
zurück zur Übersicht