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M80: Development of broadly nanobodies (VHH) against HIV-1 for prophylactic and therapeutic applications of HIV-1 infections

Dokumentation 2016–2020

Projektleiter:
Dr. Ursula Dietrich

Institut für Tumorbiologie und experimentelle Therapie sowie molekulare Virologie
Georg-Speyer-Haus
Paul-Ehrlich-Str. 42-44
60596 Frankfurt

Projekttitel:

Development of broadly neutralizing nanobodies (VHH) against HIV-1 for prophylactic and therapeutic applications of HIV-1 infections

Projektdauer:

01/2017 – 2019

Veröffentlichungen: 

Koch K, Kalusche S, Torres JL, Stanfield RL, Danquah W, Khazanehdari K, von Briesen H, Geertsma ER, Wilson IA, Wernery U, Koch-Nolte F, Ward AB, Dietrich U.
Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers
Scientific Reports 2017, 7:8390 doi: 10.1038/s41598-017-08273-7