M34: Identifizierung und Validierung therapeutischer Zielstrukturen bei der chronisch myeloischen Leukämie (CML)
Dokumentation 2006–2009
Projektleiter:
Prof. Dr. M. Scherr
Prof. Dr. M. Eder
Medizinische Hochschule Hannover
Zentrum Innere Medizin
Abteilung Hämatologie und Onkologie
30623 Hannover
Projekttitel:
Identifizierung und Validierung therapeutischer Zielstrukturen bei der chronisch myeloischen Leukämie (CML)
Projektdauer:
01/2006 - 1/2009
Veröffentlichungen:
- Ewa Surdziel, Matthias Eder and Michaela Scherr
Lentivirus-Mediated Antagomir Expression MicroRNAs and the Immune System: Methods and Protocols, Methods in Molecular Biology, vol. 667, DOI 10.1007/978-1-60761-811-9_16, LLC 2010 - Anuhar Chaturvedi, Karin Battmer, Daniel Schaefer, Arnold Ganser, Matthias Eder and Michaela Scherr
Comparison between Molecularly defined and conventional therapeutics in a conditional BCR-ABL Cell Culture Model
Oligonucleotides 17:000-000 (2007) - Julia Skokowa, Gunnar Cario, Murat Uenalan, Axel Schambach, Manuela Germeshausen, Kartin Battmer, Cornelia Zeidler, Ulrich Lehmann, Matthias Eder, Christopher Baum, Rudolf Grosschedl, Martin Stanulla, Michaela Scherr & Karl Welte
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
Nature Medicine (2006) - Letizia Venturini, Matthias Eder and Michaela Scherr
RNA-Mediated Gene Silencing in Hematopoietic Cells Journal of Biomedicine and Biotechnology (2006) - Michaela Scherr, Annuhar Chaturvedi, Karin Battmer, Iris Dallmann, Beate Schultheis, Arnold Ganser and Matthias Eder
Enhanced sensitivity to inhibition of SHP2, STAT5, and Gab2 expression in chronic myeloid leukaemia (CML)
Blood, 15. April 2006, Volume 107, Number 8 - Letizia Venturini, Karin Battmer, Mirco Castoldi, Beate Schultheis, Andreas Hochhaus, Martina U. Muckenthaler, Arnold Ganser, Matthias Eder and Michaela Scherr
Expression of the miR-17-92 polycistron in chronic myeloid leukaemia (CML) CD34+ cells
Blood, 15. May 2007, Volume 109, Number 10 - Michaela Scherr, Matthias Eder
Gene Silencing by Small Regulatory RNAs in Mammalian Cells
Cell Cycle 2007; Vol.6 Issue 4 - A.Koch, M. Scherr, Breyer, A. Mancini, C. Kardinal, K. Battmer, M. Eder and T. Tamura
Inhibition of Abl tyrosine kinase enhances nerve growth factor-mediated signaling in Bcr-Abl transformed cells via the alteration of signaling complex and the receptor turnover
Oncogene (2008) 1-12 - Lentivirus-mediated antagomir expression for specific inhibition of miRNA function
Scherr, Letizia Venturini, Karin Batmer, Michael Schaller-Schoenitz, Daniel Schaefer, Iris Dallmannm, Arnold Ganser and Andreas Eder
Nucleic Acids Research 2007, Vol. 35, No. 22 e149
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